It was developed as a prescription medicine for treating severe pain, such as pain after surgery. However, people may not always know fentanyl is present. Fentanyl is an opioid pain reliever for use in medical treatment. Although healthcare professionals consider fentanyl safe and effective when a person uses it in a monitored medical setting, the drug carries a high potential for misuse, also known as abuse. Investigators were able to link the sellers to seven U.S. related opioid-related overdose deaths and 18 arrests for drug related offenses. They were also able to identify suspected distribution networks that transship purchases into the U.S. from China.
It is an effective medication for managing severe pain when properly prescribed and monitored by a clinician. Naloxone — also known by the brand names such as Narcan and Kloxxado — is a prescription medication that reverses an opioid overdose. While it works quickly, naloxone is a temporary solution that works for 30 to 90 minutes. It’s available both for those who have been prescribed fentanyl and those who are misusing fentanyl. Naloxone may be available without a prescription at community-based programs, local public health groups or local health departments. In many states, the medicine may be requested from a pharmacy without a patient-specific prescription.

Be sure to schedule appointments with your doctor on a regular basis so that you do not run out of medication. Call your doctor if you have any unusual problems while using this medication. If your loved one is struggling with opioid use, the resources below may be helpful.
For continuous delivery, a transdermal patch can slowly deliver fentanyl through the skin and into the bloodstream for up to 72 hours. The report was critical of the U.S Postal Service and the U.S. Customs and Border Protection for failing to recognize and prepare for the increase in international shipments. Investigators tracked several shipments to individuals who sent money to the six online sellers. One of the people they tracked was a 49-year-old Ohio resident who sent about $2,500 over the course of a 10-month period. He died in early 2017 from “acute fentanyl intoxication,” just about 30 days after receiving the last of 15 packages through the Postal Service.
Why Is Fentanyl Dangerous?

Common pharmaceutical industry fentanyl analogs used during surgery include sufentanil (Sufenta), alfentanil (Alfenta) and remifentanil (Ultiva). There are more than 30 nonpharmaceutical-grade fentanyl analogs circulating on the illicit drug market, many of which cannot be detected on standard urine drug screens. First responders will likely administer naloxone if you haven’t already, or give it to them again.
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- When someone with an opioid use disorder misuses fentanyl, it is usually illegally manufactured fentanyl rather than a prescription product.
- The effects of fentanyl last a few hours, but it can be detected in your urine, hair and blood far longer.
- After you talk with your doctor, you will sign a form acknowledging that you understand the risks of using fentanyl and that you will follow your doctor’s instructions to use the medication safely.
- “The federal government can, and must, act to shore up our defenses against this deadly drug and help save lives,” Portman said.
- Do not let anyone else use your medication, even if he or she has the same symptoms that you have.
His brother reported that the boy had taken a blue tablet labeled “M30,” which the boy believed to be oxycodone. A urine test was positive for both fentanyl and cocaine (from Joynt & Wand, 2021). Fentanyl can be made into pills or powders, which can unknowingly get mixed into other drugs. In case of overdose, remove the fentanyl from the victim’s mouth and call local emergency services at 911. Do not stop using fentanyl without talking to your doctor. If you suddenly stop using fentanyl, you may experience unpleasant withdrawal symptoms.
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The fentanyl we see in the US drug supply mostly comes from Mexico and China. Pharmaceutical fentanyl is used to treat post-op pain, cancer patients and others with severe chronic pain. A 26-year-old man with a history of fentanyl abuse was found unresponsive in a gas station bathroom. Bystanders administered naloxone and performed CPR until an ambulance arrived. He was taken to a hospital, where he spent 3 days in the intensive care unit. He went on to recover and was discharged to a rehabilitation program.
What If I Miss A Dose?
- It can cause harm or death to people with opioid use disorders or who may have accidental exposure to the drug.
- A program has been set up for each fentanyl product to decrease the risk of using the medication.
- Prescription fentanyl is FDA -approved to treat severe pain related to surgery or complex pain conditions.
- After a fentanyl treatment, you may have side effects that hinder your thinking and reactions or cause dizziness or drowsiness.
- Recovery is possible with the proper support and treatment.
Contact a treatment provider today to learn more about your treatment options. Fentanyl is in a class of medications called narcotic (opiate) analgesics. It works by changing the way the brain and nervous system respond to pain. A program has been set up for each fentanyl product to decrease the risk of using the medication.
What Is Fentanyl’s Role In The Overdose And Addiction Crisis?
Fentanyl may cause serious breathing problems or death if it is used by people who are not being treated with other narcotic medications or who are not tolerant to narcotic medications. Fentanyl exerts its pain-relieving effects by acting on opioid receptors that occur naturally in the body. Endorphins, the substances in the body that normally bind to opioid receptors and naturally relieve pain, are also connected with “pleasure centers” in the brain. Repeated activation of these centers by narcotic drugs is suspected of playing a role in drug addiction. Hence, fentanyl, similar to other narcotic drugs, carries a high risk of addiction and accidental overdose.

How To Use Fentanyl Safely
Talk to your doctor about how well the medication is working and whether you are experiencing any side effects so that your doctor can decide whether your dose should be adjusted. Do not take more of it or take it more often than prescribed by your doctor. Fentanyl may cause serious harm or death if used accidentally by a child or by an adult who has not been prescribed the medication. Even partially used fentanyl may contain enough medication to cause serious harm or death to children or other adults. Dispose of partially used lozenges according to the manufacturer’s directions immediately after you remove them from your mouth. If fentanyl is used by a child or an adult who has not been prescribed the medication, try to remove the medication from the person’s mouth and get emergency medical help.


If you breastfeed while taking this medication, seek medical care right away if you notice the child has slow or noisy breathing, is unusually sleepy or not able to wake up, or is limp. If you live in King County you may be able to order free fentanyl test strips through an online order form. Fentanyl overdose often comes on much faster and stronger than a typical opioid overdose.
How Can I Find Out If My Drugs Or Pills Contain Fentanyl?
Fentanyl should be used along with your other pain medication(s). Do not stop taking your other pain medication(s) when you begin your treatment with fentanyl. If you stop taking your other pain medication(s) you will need to stop using fentanyl.
Naloxone only works in the body for 30 to 90 minutes, so it’s possible for someone to still have overdose effects after the medication wears off or needs multiple doses. While it’s safe for your doctor to give you fentanyl in a medical setting, some people abuse it, which can lead to an overdose. Drugs may contain deadly levels of fentanyl, and you wouldn’t be able to see it, taste it, or smell it.
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Fentanyl’s strength increases this risk of overdose substantially. Synthetic opioids sold illicitly can be mixed with heroin or cocaine, which amplifies its potency and potential danger. This is particularly dangerous if an individual who uses illegal substances like heroin or intentionally misuses prescription drugs is unaware that fentanyl could be in it. Prescription fentanyl is FDA -approved to treat severe pain related to surgery or complex pain conditions.